Search
magnifying-glass
51 Insights
Log in
Subscribe
Home
Archive
Tags
Insights
Subscribe
51 Insights
Zach Pandl: Why Grayscale Says It's Time to Buy Bitcoin

Nov 5, 2026

Zach Pandl: Why Grayscale Says It's Time to Buy Bitcoin

Zach Pandl: Why Grayscale Says It's Time to Buy Bitcoin
00:00
55:06

Zach Pandl, Head of Research at Grayscale, on why Grayscale gave clients the green light to buy Bitcoin, why he thinks the June low marked the bottom, and why Bitcoin rallied even after the Fed hiked and the CLARITY Act stalled.

In this episode of 51 Insights, Marc Baumann speaks with Zach Pandl about whether the four-year cycle still holds, why the big crypto assets trade like commodities, how the ETFs lowered the risk for allocators, interest rates and Bitcoin, Strategy's balance sheet, how a Goldman Sachs FX strategist ended up in Bitcoin, the debasement trade and what to own beyond Bitcoin, why transaction fees are the best single measure of a layer one, the fat protocol thesis, Ethereum, Solana, BNB, Sui and Avalanche, why central banks buy gold and not Bitcoin, privacy and Zcash, quantum computing, the AI compute layer and Bitcoin miners, crypto AI tokens like NEAR and Bittensor, and being wrong in public.

Watch or listen to the full 51 Insights podcast:
https://www.51insights.xyz

CHAPTERS
00:00 Introduction
01:29 The green light to buy Bitcoin
03:35 Is the four-year cycle dead?
06:35 What's different this cycle: lower risk and the ETFs
10:28 Why Bitcoin is rising after a Fed hike
13:41 Strategy, leverage and the recent rally
14:52 From Goldman Sachs FX strategist to Bitcoin
18:08 The debasement trade and what to own beyond Bitcoin
21:54 Stablecoins and where crypto fees accrue
24:03 Transaction fees: the desert island indicator
26:39 Is the fat protocol thesis dead?
30:22 Ethereum, Solana, BNB and the next layer-one leaders
31:44 A multi-chain world with strong network effects
33:15 Why central banks buy gold, not Bitcoin
36:11 Privacy and the Zcash case
38:10 Quantum computing and Bitcoin
42:02 Where we are in the AI build-out
44:47 Bitcoin miners and the AI compute layer
46:28 Why crypto AI tokens rallied
48:45 NEAR and Bittensor
50:29 The most mispriced asset: Zcash
51:49 Being wrong in public
52:38 Lightning round

ABOUT ZACH PANDL
Zach Pandl is Head of Research at Grayscale, where he writes The Stack, the firm's research blog. Before Grayscale he spent close to two decades as a macroeconomist and markets strategist on Wall Street at Lehman Brothers, Nomura Securities and Goldman Sachs, where he was co-head of global foreign exchange, rates and emerging markets strategy. He holds a bachelor's degree in international economics from the University of St. Thomas and a master's degree in economics from New York University.

LINKS
The Stack: https://www.grayscale.com/the-stack
X: https://x.com/LowBeta
51 Insights: https://www.51insights.xyz
Newsletter: https://join.fiftyone.xyz

CORRECTIONS
- 01:17 and 01:36: Grayscale's "green light" call to clients came in mid-September 2026, right after the September 16 Fed hike and the September 15 CLARITY Act vote. That was about five weeks before this conversation was recorded, not a week.

ABOUT 51 INSIGHTS
51 Insights provides institutional research and conversations on digital assets, AI, finance, and emerging technology.

Transcript

51 Insights – What's next in digital assets, AI and markets.

Listen on

Apple PodcastsApple PodcastsSpotifySpotifyYouTubeYouTubePocket CastsPocket CastsCastroCastro

Recent episodes

Chris Giancarlo: "The Real Choice Will Be Freedom or Control"

Chris Giancarlo: "The Real Choice Will Be Freedom or Control"

Oct 28, 2026

Jeff Booth: Money Is Theft and the Debt Can't Be Repaid

Jeff Booth: Money Is Theft and the Debt Can't Be Repaid

Oct 26, 2026

Matt Hougan: If the AI Trade Breaks, Bitcoin Is a Generational Buy

Matt Hougan: If the AI Trade Breaks, Bitcoin Is a Generational Buy

Oct 15, 2026

Tokenizing $100T in Treasuries and equities without breaking the market, with Nadine Chakar

Tokenizing $100T in Treasuries and equities without breaking the market, with Nadine Chakar

Sep 30, 2026

Scott Melker (Wolf of All Streets): Clarity, Robinhood, XRP, $250K Bitcoin

Scott Melker (Wolf of All Streets): Clarity, Robinhood, XRP, $250K Bitcoin

Sep 22, 2026

The Next Trillion Dollar Crypto Opportunity with Anthony B. (Coinbase Asset Management)

The Next Trillion Dollar Crypto Opportunity with Anthony B. (Coinbase Asset Management)

Aug 27, 2026

The $2T market still running on spreadsheets

The $2T market still running on spreadsheets

Aug 20, 2026

why a KKR partner left for DeFi (with Xiao-Xiao, President of Jupiter)

why a KKR partner left for DeFi (with Xiao-Xiao, President of Jupiter)

Aug 12, 2026

"waiting isn't a strategy", with Christian Schmid, Global Banking Lead, BCG

"waiting isn't a strategy", with Christian Schmid, Global Banking Lead, BCG

Aug 5, 2026

"Europe's biggest problem is Europe", with Michael Every, Global Strategist at Rabobank

"Europe's biggest problem is Europe", with Michael Every, Global Strategist at Rabobank

Jul 28, 2026

51 Insights

Join the list to receive our newest posts straight to your inbox.

51 Insights

The only institutional digital assets intelligence worth acting on. Join 35k+ industry leaders and save 10+ hours or get one insight worth 100x your subscription in 30 days.

Home

Subscribe

Archive

Tags

Authors

Login

Reset Password

Update Password

Profile

Search

© 2026 Fiftyone Group LLC.
beehiivPowered by beehiiv